Skinbetter Science Alpharet Overnight Face Cream


A unique combination of an alpha hydroxy acid (AHA) and a retinoid that provides visible skin rejuvenation with little-to-no irritation. Improves the appearance of lines, wrinkles, uneven tone and texture. AlphaRet is the latest innovation in retinoid renewal delivering remarkable results, with little-to-no irritation compared to other retinoids and retinoid-based products.

Glycolic acid helps retexturize to increase the efficacy of AlphaRet. Our deeply hydrating formula also contains a powerhouse of peptides and antioxidants to help protect against free radicals. A trilogy of skin soothing ingredients helps keep skin balanced. With consistent nightly use, skin improvement is visible in as little as four weeks.

  • Significantly reduces the appearance of wrinkles in as little as four weeks, with little-to-no irritation.
  • Combines two gold standard skin rejuvenation ingredients— a retinoid and lactic acid—to create a revolutionary double-conjugated retinoid.
  • Provides moisture to help counteract dryness associated with traditional retinoid-based products.
  • A blend of antioxidants helps neutralize free radicals.

13 in stock (can be backordered)

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Additional information


• A significant reduction in the appearance of depth and size of wrinkles in as little as four weeks,* with little to no irritation.
• Proprietary and revolutionary AlphaRet, a new skin rejuvenating technology, is the result of combining two gold standard anti-aging ingredients, a retinoid and alpha hydroxy acid, to create a revolutionary double conjugated retinoid.
• Glycolic acid helps increase the efficacy of AlphaRet.
• A targeted peptide blend acts synergistically with AlphaRet resulting in fewer visible age lines.
• An ultra hydrating blend of squalane niacinamide, ceramides, fatty acids provides deep moisture to help counteract the dryness associated with traditional retinoid based products.
• A trilogy of skin soothing ingredients including allantoin glycyrrhetinic acid, bisabolol and portulaca extract provides a sensation of calmness.
• A potent blend of antioxidants helps provide protection against free radicals.


• Laxity
• Texture
• Fine lines
• Acne
• Acne scarring
• Pigmentation
• Expression lines
• Dry skin

Key Ingredients

• AlphaRet – Delivers maximum retinoid efficacy with little to no irritation.
• Glycolic Acid – Helps retexturise the skin to increase efficacy of AlphaRet.
• Blend of three unique Peptides – Promotes wrinkle-smoothing and improves skin tone and density.
• Bisabolol and Portulaca Extract – Helps reduce the appearance of redness and calms the skin.
• Antioxidants (Green Tea, Co-enzyme Q10 and Vitamin E) – Provides protective benefits.
• Sodium PCA and Hyaluronic Acid – Provides moisturisation benefits.


• Allure Magazine "Breakthrough Award" Winner
• InStyle Magazine “Best Beauty Buy”
• Cosmopolitan Skin Awards “Best of Class”

Product Size

1.0 FL OZ / 30 ML


Skinbetter science products are sold only through physician practices and authorized medical spas. The link provided to purchase Skinbetter products is intended only for use by existing Skinbetter science users, or patients that have otherwise received a skin consultation by Cadella Med Spa.