Skinbetter Science Alpharet Clearing Serum


Improves the appearance of skin clarity, pores and overall tone and texture. Patented AlphaRet technology, now in a uniquely formulated serum, is designed for those wishing to maintain a youthful-looking complexion and clarify the appearance of oilier, blemish-prone skin.

Patented retinoid technology, AlphaRet, is formulated with salicylic acid and additional pore-clearing, hydrating and soothing ingredients, to rejuvenate and clarify the appearance of oiler, blemish-prone skin.

  • Improvement in the appearance of skin clarity, pores, skin surface shine, and overall tone and texture.
  • Smoother, more even-looking complexion.
  • Healthier-looking skin, with little-to-no dryness or flaking.

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Additional information


• A significant reduction in the appearance of depth and size of wrinkles in as little as four weeks,* with little to no irritation.
• Proprietary and revolutionary AlphaRet, a new skin rejuvenating technology, is the result of combining two gold standard anti-aging ingredients, a retinoid and alpha hydroxy acid, to create a revolutionary double conjugated retinoid.
• Glycolic acid helps increase the efficacy of AlphaRet.
• A targeted peptide blend acts synergistically with AlphaRet resulting in fewer visible age lines.
• An ultra hydrating blend of squalane niacinamide, ceramides, fatty acids provides deep moisture to help counteract the dryness associated with traditional retinoid based products.
• A trilogy of skin soothing ingredients including allantoin glycyrrhetinic acid, bisabolol and portulaca extract provides a sensation of calmness.
• A potent blend of antioxidants helps provide protection against free radicals.

Key Ingredients

It delivers glycolic acid with a stabilized form of retinol to enhance exfoliation, cell turnover, and collagen production, which translates to a brighter complexion and improved skin texture.

In addition to its two hero ingredients, the cream also contains peptides, which improve tone and elasticity, and antioxidants to defend against the environmental and free radical damage. So, essentially, it’s got everything.

Doctor's Endorsement

"I’m a Dermatologist, and This Powerful Skin-Care Serum Is Like Microdermabrasion in a Bottle. Thanks to this potent formula, fine lines—and other textural issues—don’t stand much of a chance."
– ★★★★★ Zoe Weiner, MD

Customer Reviews

"Finally : a retinol ccream that doesn't irritate my sensitive skin! I've been using it for a little over a month, and while at 27 years old I don't really have any significant wrinkles to report on, I've noticed my skin feels much smoother. The tone, which was a little blotchy before, has evened out a noticeable amount, too."
– ★★★★★ Victoria Moorhouse, InStyle Magazine + Verified Customer

How to Use

• Apply in the PM, before bed
• Apply a thin layer all over the face at night.
• May be applied following InterFuse® Intensive Treatment LINES.
• Can be used in combination with Even Tone Correcting Serum™ to target improvement in the appearance of hyperpigmentation.
• Intensive AlphaRet Overnight Cream contains a topical retinoid. We recommend consulting your physician before use if you are pregnant, lactating, or planning to become pregnant.

Product Size

1.0 FL OZ / 30 ML


Skinbetter science products are sold only through physician practices and authorized medical spas. The link provided to purchase Skinbetter products is intended only for use by existing Skinbetter science users, or patients that have otherwise received a skin consultation by Cadella Med Spa.