Botox for Hyperhidrosis


Botox is used to temporarily block the secretion of sweat, particularly in the underarms and palms of the hands.

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Botox has the ability to temporarily block the secretion of the chemical that is responsible for stimulating the body’s sweat glands. By interrupting this chemical messenger, the botulinum toxin inhibits sweating in the area where it has been injected. Common areas for botox injections for hyperhidrosis include the underarms and palms of the hands.

About the Procedure

Botox injections are commonly used to inhibit muscle movement to prevent wrinkles and fines lines from forming however, the naturally derived toxin can also be used to temporarily chemo-denervate the eccrine glands involved in hyperhidrosis. Typically, 50-100 units of Botox will be injected into each underarm for treatment. The cumulative dose of botox should not exceed 360 units in a three-month period, as recommended by the FDA. In order to determine the area to be injected, a starch iodine test will be administered to determine the location of the sweat glands. Alternatively, areas may be marked for injection based off of the hair-bearing area. Approximately 40 evenly-distributed injection sites are placed in each underarm, with the injection sites being 8 mm apart. Once inserted, the syringe will deposit approximately 0.05 mL of the solution subdermally, after which it is withdrawn. While only FDA approved for treatment of overactive sweat glands in the axilla, it is common for botox to be injected into the palms of the hands and soles of the feet for hyperhidrosis treatment as well.

Commonly Treated Concerns

Typical Cost Range

$1000 – $1500

Ideal Candidate

Botox injections are not recommended for patients under the age of 18.

Additional information

Average Cost


Cost Range

$1000 – $1500





Procedure Pros

• no downtime
• quick results

Procedure Cons

• temporary
• multiple treatments

Recovery Notes

The ideal candidate for botox injections for hyperhidrosis experiences severe underarm sweating that impacts quality of life.

Recovery Time

1 days

Surgical (Y/N)

Nonsurgical / Noninvasive